This is the timeline of antimicrobial (anti-infective) therapy. The years show when a given drug was released onto the pharmaceutical market. This is not a timeline of the development of the antibiotics themselves.
1911 - Arsphenamine aka Salvarsan[1]
1912 - Neosalvarsan
1935 - Prontosil (an oral precursor to sulfanilimide), the first sulfonamide
1936 - Sulfanilimide
1938 - Sulfapyridine (M&B 693)
1939 - sulfacetamide
1940 - sulfamethizole
1942 - benzylpenicillin, the first penicillin
1942 - gramicidin S, the first peptide antibiotic
1942 - sulfadimidine
1943 - sulfamerazine
1944 - streptomycin, the first aminoglycoside[2]
1947 - sulfadiazine
1948 - chlortetracycline, the first tetracycline
1949 - chloramphenicol, the first amphenicol[2]
1949 - neomycin
1950 - oxytetracycline
1950 - penicillin G procaine
1952 - erythromycin, the first macrolide[2]
1954 - benzathine penicillin
1955 - spiramycin
1955 - tetracycline
1955 - thiamphenicol
1955 - vancomycin, the first glycopeptide
1956 - phenoxymethylpenicillin
1958 - colistin, the first polymyxin
1958 - demeclocycline
1959 - virginiamycin
1960 - methicillin
1960 - metronidazole, the first nitroimidazole
1961 - ampicillin
1961 - spectinomycin
1961 - sulfamethoxazole
1961 - trimethoprim, the first dihydrofolate reductase inhibitor
1962 - cloxacillin
1962 - fusidic acid
1963 - fusafungine
1963 - lymecycline
1964 - gentamicin
1964 - Cefalotin, the first cephalosporin
1966 - doxycycline
1967 - carbenicillin
1967 - rifampicin
1967 - Nalidixic acid, the first quinolone
1968 - clindamycin, the second lincosamide
1970 - cefalexin
1971 - cefazolin
1971 - pivampicillin
1971 - tinidazole
1972 - amoxicillin
1972 - cefradine
1972 - minocycline
1972 - pristinamycin
1973 - fosfomycin
1974 - talampicillin
1975 - tobramycin
1975 - bacampicillin
1975 - ticarcillin
1976 - amikacin
1977 - azlocillin
1977 - cefadroxil
1977 - cefamandole
1977 - cefoxitin
1977 - cefuroxime
1977 - mezlocillin
1977 - pivmecillinam
From 1978
1979 - cefaclor
1980 - cefmetazole
1980 - cefotaxime
1980 - cefsulodin
1980 - piperacillin
1981 - co-amoxiclav (amoxicillin/clavulanic acid)
1981 - cefoperazone
1981 - cefotiam
1981 - cefsulodin
1981 - latamoxef
1981 - netilmicin
1982 - ceftriaxone
1982 - micronomicin
1983 - cefmenoxime
1983 - ceftazidime
1983 - ceftizoxime
1983 - norfloxacin
1984 - cefonicid
1984 - cefotetan
1984 - temocillin
1985 - cefpiramide
1985 - imipenem/cilastatin, the first carbapenem
1985 - ofloxacin
1986 - mupirocin
1986 - aztreonam
1986 - cefoperazone/sulbactam
1986 - co-ticarclav (ticarcillin/clavulanic acid)
1987 - ampicillin/sulbactam
1987 - cefixime
1987 - roxithromycin
1987 - sultamicillin
1987 - ciprofloxacin, the first 2nd-gen fluoroquinolone
1987 - rifaximin, the first ansamycin
1988 - azithromycin
1988 - flomoxef
1988 - isepamycin
1988 - midecamycin
1988 - rifapentine
1988 - teicoplanin
1989 - cefpodoxime
1989 - enrofloxacin
1989 - lomefloxacin
1989 - moxifloxacin
1990 - arbekacin
1990 - cefozidime
1990 - clarithromycin
1991 - cefdinir
1992 - cefetamet
1992 - cefpirome
1992 - cefprozil
1992 - ceftibuten
1992 - fleroxacin
1992 - loracarbef
1992 - piperacillin/tazobactam
1992 - rufloxacin
1993 - brodimoprim
1993 - dirithromycin
1993 - levofloxacin
1993 - nadifloxacin
1993 - panipenem/betamipron
1993 - sparfloxacin
1994 - cefepime
1999 - quinupristin/dalfopristin
2000 - linezolid, the first oxazolidinone
2001 - telithromycin, the first ketolide
2003 - daptomycin
2005 - tigecycline
2005 - doripenem
2009 - telavancin, the first Lipoglycopeptide
2010 - ceftaroline
2011 - fidaxomicin
2012 - bedaquiline
2013 - telavancin
2014 - tedizolid
2014 - dalbavancin
2015 - ceftolozane/tazobactam
See also
Timeline of medicine and medical technology
List of antibiotics, grouped by class
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楼主: 王志新
发表于 2016-5-7 10:52:20
